Electrochemical study of complexes of Co (II) with Antibiotic Drug Benzyl Penicillin sodium salt at d.m.e

Polarographic technique has been used to evaluate the kinetic parameters and formation constants of Co (П) complexes with benzyl penicillin sodium salt at pH 6.0±0.10 and constant ionic strength (μ = 0.1), HCl in aqueous, aqueous-methanol and aqueous-ethanol mixtures at d.m.e. The effect of concentration and temperature on the half wave potential of the complexes has also been investigated. The reduction of all these complexes is found to be irreversible and diffusion controlled, hence kinetic parameters (Kfh, αn) of these complexes have been calculated using Meites-Isral method and its modification by Gaur and Bhargava. In all the cases single reduction wave is obtained.